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This does not mean that the medicine is not working If you get ill while taking it. 9k views Answered >2 years ago. Added 16 Aug 2010: I did not feel bad the first week, just the last 2. Lisinopril may be known by the brand names Prinivil or Zestril, though it is now most often used as a generic drug. This does not mean that the medicine is not working Lisinopril: In general you don't need to wean off lisinopril, but you should ask your doctor. In these cases, you may not feel any different when you take lisinopril. Further, high blood pressure can result in a heart attack, vision loss, heart failure, kidney failure, sexual dysfunction, stroke, and possible other long term affects. (if your blood pressure is very low then do not take. I must admit pretty much every day I've taken the pill after I've eaten my breakfast and swallowed it with my morning cup of coffee Very rarely, people can have a bad reaction to amlodipine. 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